Amphotericin B-impregnated bone cement to treat refractory coccidioidal osteomyelitis.

نویسندگان

  • Elizabeth S Zhu
  • George R Thompson
  • Christopher Kreulen
  • Eric Giza
چکیده

Use of amphotericin B-impregnated bone cement in combination with systemic antifungals for the treatment of coccidioidal osteomyelitis offers the potential for sustained local concentrations of drug at the site of the infection. Amphotericin B levels in bone of up to 5.1 μg/g have been demonstrated 4 months after placement of bone cement.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 57 12  شماره 

صفحات  -

تاریخ انتشار 2013